Endocrine Abstracts

Objective: In chronic hypoparathyroidism, conventional therapy consists of oral calcium supplements and active vitamin D analogs but some patients cannot achieve treatment goals despite the high dose of oral calcium supplementation. Therefore, parathyroid gland transplantation and recombinant human PTH have been investigating as new therapeutic options. Calcium absorption from intestinal cells occurs by transcellular path and paracellular path. Transcellular absorption occurs ...

Introduction: Papillary thyroid carcinoma (PTC) is the most common endocrine cancer however extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT) of the thyroid gland is quite rare. The simultaneous association of both cancers is much more rare.Case report: 65-year-old woman underwent a thyroid ultrasound examination due to palpable thyroid nodules. Thyroid ultrasound revealed thyroiditis and multiple nodules on the right and ...

Aim: The etiology and underlying pathology of non-functional adrenal adenoma has not been clearly defined, yet. Blood pressure levels according to adrenal adenoma size has not been evaluated, yet. Therefore, we evaluated 24 hour ambulatory blood pressure levels in patients with non functional adrenal adenoma.Materials & Methods: We studied thirty newly diagnosed adrenal adenoma patients in a tertiary health-care center. They grouped in two categories...

Introduction: In recent years, it is thought that cardiovascular risk is increased in patients with nonfunctional adrenal insidentaloma (NFAI). There are not enough studies in the literature that evaluating this condition in patients with NFAI who don’t have traditional cardiovascular risk factors. The aim of our study is to determine peripheral and central blood pressures and arterial stiffness in patients with NFAI who don’t have traditional risk factors and autono...

Introduction: Thyrotropinomas are usually considered when the TSH level is inappropriately elevated or normal in a hyperthyroid patient with increased serum T4 levels, regardless of the presence of visible tumor on imaging. The prevalence of these adenomas, which account for 0.5–3% of all pituitary tumors has been estimated to be around one case per million. Most thyrotroph adenomas are large and invasive at diagnosis, and present with signs and symptoms of an ...

Introduction: Acromegaly is a chronical and rare disease which is accompanied by excessive growth hormone (GH) secreting hypohysis tumor. In this study we presented acromegaly patients’ datas who admitted to our center between the years 1998–2016. We discussed patients’ charecteristics and we aimed to investigate the determinants which is effecting the remission rate of the patients’.Method: 70 acromegaly patients datas were analyzed ...

Introduction: In a recent study, it was determined that morbidity rates due to cardiovascular diseases were affected as a result of long-term follow-up in patients with nonfunctional pituitary adenoma. And cardio/cerebro vascular diseases were the most frequent cause of mortality when mortality rates were examined. In the literature, there are not enough studies evaluating this condition in patients with nonfunctional pituitary adenoma without traditional cardiovascular risk f...

Background and aim: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder in women with reproductive age. Nodular goiter and autoimmune thyroid disease (AITD) are frequently seen endocrinological abnormalities. The aim of this study was to identify the prevalence of AITD and nodular goiter in PCOS patients and investigate whether PCOS related hormones and metabolic factors affect these thyroid disorders.Methods: Ninety-seven with ...

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine pathology in premenopausal women and it is a complex syndrome affecting various systems. Numerous studies have been made about how the PCOS effects on bone metabolism, but currently there is no clear information. Wnt pathway plays important role in the regulation of bone metabolism. The sclerostin(Scl) and Dickkopf-1 (DKK1) inhibit this pathway and they has recently become a therapeutic target of osteo...

Aims: Because of an increased metabolic activity and thermogenesis in hyperthyroidism, we aimed to evaluate the association of serum irisin with thyroid hormones.Methods: A total of 25 hyperthyroid patients and 24 age- and gender-matched healthy controls were enrolled. Serum irisin levels, thyroid hormones and body compositions were analyzed.Results: Serum irisin levels were significantly higher in hyperthyroid group (P&#6...